Iitaka M, Momotani N, Ishii J, Ito K
Fourth Department of Internal Medicine, Saitama Medical School, Ito Hospital, Japan.
J Clin Endocrinol Metab. 1996 Feb;81(2):466-9. doi: 10.1210/jcem.81.2.8636251.
Subacute thyroiditis, which is considered to be a viral disease, rarely recurs after a complete recovery. We evaluated data on 3,344 patients with subacute thyroiditis who were seen at Ito Hospital between 1970 and 1993. Subacute thyroiditis recurred in 48 of 3,344 patients 14.5 +/- 4.5 yr after the first episode. Five patients experienced a third episode 7.6 +/- 2.4 yr after the second. The mean age of the patients at the first, second, and third episode was 38.4 +/- 6.3, 53.1 +/- 8.9, and 57.8 +/- 10.1 yr old, respectively. The mean incidence of a recurrence was 2.3 +/- 0.9% per year. The erythrocyte sedimentation rate and the duration of treatment were each significantly decreased at the second episode as compared with the first. Thus, recurrences of subacute thyroiditis do occur at least in 2% of patients and exhibited relatively mild clinical manifestations.
亚急性甲状腺炎被认为是一种病毒性疾病，完全康复后很少复发。我们评估了1970年至1993年间在伊藤医院就诊的3344例亚急性甲状腺炎患者的数据。3344例患者中，48例在首次发病后14.5±4.5年复发。5例患者在第二次发病后7.6±2.4年经历了第三次发作。患者第一次、第二次和第三次发作时的平均年龄分别为38.4±6.3岁、53.1±8.9岁和57.8±10.1岁。复发的平均发生率为每年2.3±0.9%。与第一次发作相比，第二次发作时红细胞沉降率和治疗持续时间均显著降低。因此，亚急性甲状腺炎至少在2%的患者中会复发，且临床表现相对较轻。
