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[体外受精失败或成功后夫妻的自然受孕情况]

[Spontaneous pregnancies in couples after failed or successful in vitro fertilization].

作者信息

Vardon D, Burban C, Collomb J, Stolla V, Erny R

机构信息

Centre de Procréation Médicalement Assistée, Hôpital de la Conception, Marseille.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1995;24(8):811-5.

PMID:8636613
Abstract

OBJECTIVE

To determinate the true incidence of treatment-independent pregnancy in an in vitro fertilization programme. To establish and to compare the characteristics of couples with and without spontaneous pregnancy. To analyze the outcome of pregnancies.

TYPE OF STUDY

Retrospective.

SETTING

In Vitro Fertilization Unit, Conception's Hospital, Marseille, France.

SUBJECTS

594 couples having attempted one or more IVF procedures. The study concerned low-fertility couples (484) ruling our true sterile couples (110).

RESULTS

Spontaneous pregnancies occurred in 54 couples (11.2%). The characteristics of the two populations were not statistically different, except a shorter duration of infertility (p < 0.05) in spontaneous pregnancies. The rate of ectopic pregnancies in the spontaneous pregnancies was statistically higher than that observed in IVP pregnancies (12% versus 6.5%). The fertility rare of these couples was very low (0.38%).

CONCLUSION

Spontaneous pregnancies in vitro fertilization programmes are not rare. The evaluation of the results of the in vitro fertilization requires taking the possible spontaneous pregnancies into account.

摘要

目的

确定体外受精项目中无需治疗而自然怀孕的真实发生率。确定并比较自然怀孕和未自然怀孕夫妇的特征。分析妊娠结局。

研究类型

回顾性研究。

研究地点

法国马赛受孕医院体外受精科。

研究对象

594对尝试过一次或多次体外受精程序的夫妇。该研究针对低生育力夫妇(484对),排除了真正的不育夫妇(110对)。

结果

54对夫妇自然怀孕(11.2%)。除自然怀孕的不孕持续时间较短(p < 0.05)外,这两组人群的特征无统计学差异。自然怀孕中宫外孕的发生率在统计学上高于体外受精怀孕中的发生率(12%对6.5%)。这些夫妇的生育几率非常低(0.38%)。

结论

体外受精项目中的自然怀孕并不罕见。体外受精结果的评估需要考虑到可能的自然怀孕情况。

相似文献

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[Spontaneous pregnancies in couples after failed or successful in vitro fertilization].[体外受精失败或成功后夫妻的自然受孕情况]
J Gynecol Obstet Biol Reprod (Paris). 1995;24(8):811-5.
2
[Perinatal results in pregnancies obtained with embryo transfer in vitro fertilization: a case-control study].[体外受精胚胎移植妊娠的围产期结局:一项病例对照研究]
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Obstetric outcome.产科结局
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In vitro fertilization and embryo transfer: a randomized controlled trial.体外受精与胚胎移植:一项随机对照试验。
Online J Curr Clin Trials. 1993 Jul 2;Doc No 73:[3483 words; 37 paragraphs].
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Rates and outcome of pregnancies achieved in the first 4 years of an in-vitro fertilization program.体外受精项目头4年的妊娠率及妊娠结局。
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Increased time-to-pregnancy and first trimester Down's syndrome screening.妊娠时间延长和孕早期唐氏综合征筛查。
Hum Reprod. 2010 Feb;25(2):412-7. doi: 10.1093/humrep/dep417. Epub 2009 Nov 26.
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Treatment-related and treatment-independent deliveries among infertile couples, a long-term follow-up.不育夫妇中与治疗相关和与治疗无关的分娩情况:一项长期随访研究
Acta Obstet Gynecol Scand. 1997 Mar;76(3):238-43.
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In-vitro fertilization pregnancies in Australia and New Zealand, 1979-1985. Australian In-Vitro Fertilization Collaborative Group.1979 - 1985年澳大利亚和新西兰的体外受精妊娠。澳大利亚体外受精协作组
Med J Aust. 1988 May 2;148(9):429, 432-6.
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Spontaneous pregnancies among couples previously treated by in vitro fertilization.体外受精治疗后自然妊娠。
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Pregnancy loss in pregnancies conceived after in vitro oocyte maturation, conventional in vitro fertilization, and intracytoplasmic sperm injection.体外卵母细胞成熟、常规体外受精和卵胞浆内单精子注射后受孕的妊娠丢失情况。
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引用本文的文献

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Spontaneous Conception during In Vitro Fertilization prior to Embryo Transfer without the Opportunity for Preimplantation Genetic Testing.在胚胎移植前的体外受精过程中自然受孕且没有进行植入前基因检测的机会。
Case Rep Obstet Gynecol. 2019 Aug 6;2019:1804948. doi: 10.1155/2019/1804948. eCollection 2019.
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Likelihood of natural conception following treatment by IVF.体外受精治疗后自然受孕的可能性。
J Assist Reprod Genet. 2005 Dec;22(11-12):401-5. doi: 10.1007/s10815-005-6655-y.