Santos Silva E E, Sarles J, Buts J P, Sokal E M
Department of Pediatrics, Catholic University of Louvain, Cliniques St. Luc, Brussels, Belgium.
J Pediatr. 1996 Feb;128(2):285-7. doi: 10.1016/s0022-3476(96)70412-2.
Delayed response to medical treatment sometimes leads to unnecessary liver transplantation in patients with severely decompensated Wilson disease. We report the course of five patients (mean age 13.4 years, range 11 to 15 years) with severely decompensated Wilson disease who were successfully treated medically. Prothrombin time improved after a minimum of 1 month and returned to normal within 3 months to 1 year or more.
对药物治疗反应延迟有时会导致严重失代偿性威尔逊病患者进行不必要的肝移植。我们报告了5例严重失代偿性威尔逊病患者(平均年龄13.4岁,范围11至15岁)经药物治疗成功的病程。凝血酶原时间至少在1个月后改善,并在3个月至1年或更长时间内恢复正常。