Peters L, Andrews G
Clinical Research Unit for Anxiety Disorders, University of New South Wales, St Vincent's Hospital, NSW, Australia.
Psychol Med. 1995 Nov;25(6):1269-80. doi: 10.1017/s0033291700033237.
The procedural validity of the computerized version of the Composite International Diagnostic Interview (CIDI-Auto) was examined against the consensus diagnoses of two clinicians for six anxiety disorders (agoraphobia, panic disorder (+/- agoraphobia), social phobia, simple phobia, obsessive compulsive disorder (OCD), generalized anxiety disorder (GAD) and major depressive episode (MDE)). Clinicians had available to them all data obtained over a 2- to 10-month period. Subjects were 98 patients accepted for treatment at an Anxiety Disorders Clinic, thus, all subjects had at least one of the diagnoses being examined. While the CIDI-Auto detected 88.2% of the clinician diagnoses, it identified twice as many diagnoses as did the clinicians. The sensitivity of the CIDI-Auto was above 0.85 except for GAD, which had a sensitivity of 0.29. The specificity of the CIDI-Auto was lower (range: 0.47-0.99). The agreement between the CIDI-Auto and the clinician diagnoses, as measured by intraclass kappas, ranged from poor (kappa = 0.02; GAD) to excellent (kappa = 0.81; OCD), with a fair level of agreement overall (kappa = 0.40). Canonical correlation analysis suggested that the discrepancies between the CIDI-Auto and clinicians were not due to different diagnostic distinctions being made. It is suggested that the CIDI-Auto may have a lower threshold for diagnosing anxiety disorders than do experienced clinicians. It is concluded that, in a sample where all subjects have at least one anxiety disorder diagnosis, the CIDI-Auto has acceptable validity.
针对六种焦虑症(广场恐惧症、惊恐障碍(伴或不伴广场恐惧症)、社交恐惧症、单纯恐惧症、强迫症(OCD)、广泛性焦虑症(GAD)和重度抑郁发作(MDE)),以两位临床医生的共识诊断为对照,检验了计算机化版综合国际诊断访谈(CIDI - Auto)的程序效度。临床医生可获取在2至10个月期间获得的所有数据。研究对象为98名在焦虑症诊所接受治疗的患者,因此,所有研究对象至少有一种被检查的诊断。虽然CIDI - Auto检测出了临床医生诊断的88.2%,但其识别出的诊断数量是临床医生的两倍。除GAD的敏感度为0.29外,CIDI - Auto的敏感度均高于0.85。CIDI - Auto的特异度较低(范围:0.47 - 0.99)。以组内kappa系数衡量,CIDI - Auto与临床医生诊断之间的一致性从较差(kappa = 0.02;GAD)到极好(kappa = 0.81;OCD)不等,总体一致性水平一般(kappa = 0.40)。典型相关分析表明,CIDI - Auto与临床医生之间的差异并非由于诊断标准不同所致。研究表明,CIDI - Auto诊断焦虑症的阈值可能低于经验丰富的临床医生。研究得出结论,在所有研究对象至少有一种焦虑症诊断的样本中,CIDI - Auto具有可接受的效度。