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在o,p'DDD治疗失败后，用依托泊苷（VP - 16）和顺铂治疗转移性肾上腺皮质癌。临床病例报告。

Treatment of metastatic adrenal cortical carcinoma with etoposide (VP-16) and cisplatin after failure with o,p'DDD. Clinical case reports.

作者信息

Zidan J, Shpendler M, Robinson E

机构信息

Northern Israel Oncology Center, Rambam Medical Center, Endocrinology Unit, Bnei-Zion Hospital, Haifa, Israel.

出版信息

Am J Clin Oncol. 1996 Jun;19(3):229-31. doi: 10.1097/00000421-199606000-00003.

DOI:10.1097/00000421-199606000-00003
PMID:8638530
Abstract

A 42-year-old woman with liver metastasis from adrenal cortical carcinoma was treated with mitotane (o,p'DDD) for 11 months with a minimal response. Mitotane was stopped because of severe adverse effects. Thereafter a combination of cisplatin and etoposide was given every 3 weeks. A partial response was achieved after five chemotherapy courses. Following this chemotherapy, the patient had a surgical excision of the liver metastasis and entered into a complete remission for 17 months. Etoposide plus cisplatin may be an active combination for the treatment of adrenal cortical carcinoma.

摘要

一名患有肾上腺皮质癌肝转移的42岁女性接受了米托坦（邻对滴滴滴）治疗11个月，反应甚微。因严重不良反应停用米托坦。此后每3周给予顺铂和依托泊苷联合治疗。五个化疗疗程后取得部分缓解。此次化疗后，患者接受了肝转移灶的手术切除，并实现了17个月的完全缓解。依托泊苷加顺铂可能是治疗肾上腺皮质癌的有效联合方案。

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Treatment of metastatic adrenal cortical carcinoma with etoposide (VP-16) and cisplatin after failure with o,p'DDD. Clinical case reports.在o,p'DDD治疗失败后，用依托泊苷（VP - 16）和顺铂治疗转移性肾上腺皮质癌。临床病例报告。
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Adrenal cortical carcinoma.
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Cytotoxic treatment of adrenocortical carcinoma.肾上腺皮质癌的细胞毒性治疗
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Adrenal cortical carcinoma.肾上腺皮质癌
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