Szymański W, Rogalewska A, Złotnik I, Obrzut D, Chyrek-Borowska S
Kliniki Alergologii Akademii Medycznej w Białymstoku.
Pneumonol Alergol Pol. 1995;63 Suppl 2:25-31.
The aim of this paper was to evaluate the clinical efficacy, individual tolerance and side effects of allergen extracts, a weed pollen vaccine Catalet C and a tree pollen vaccine Catalet D. The study was carried out on a group of 41 patients aged from 15 to 46 years in comparison with a placebo group (36 patients). A good tolerance, no serious side effects and a high clinical efficacy, manifested in diminution of pollinosis symptoms in more than 80% of patients was noted. In the treated patients a significant reduction of antiallergic drug consumption in the pollen season was noted as compared with the placebo. The extracts Catalet C and Catalet D are usefull in the specific immunotherapy in weed and tree pollen allergic patients.
本文旨在评估变应原提取物、一种杂草花粉疫苗Catalet C和一种树木花粉疫苗Catalet D的临床疗效、个体耐受性及副作用。该研究针对一组年龄在15至46岁的41名患者开展，并与一个安慰剂组（36名患者）进行比较。结果发现耐受性良好，无严重副作用，且临床疗效显著，超过80%的患者花粉症症状减轻。与安慰剂组相比，接受治疗的患者在花粉季节抗过敏性药物的消耗量显著减少。Catalet C和Catalet D提取物对杂草和树木花粉过敏患者的特异性免疫治疗有用。
