Chyrek-Borowska S, Szymański W, Rogalewska A, Michalska I
Kliniki Alergologii Akademii Medycznej w Białymstoku.
Pneumonol Alergol Pol. 1995;63 Suppl 2:19-24.
In a group of 41 hay fever and/or seasonal asthma patients, sensitive to weed or tree pollens the influence of specific immunotherapy (sIT) on the level of IgE, specific IgE and IgG4, and HR induced by anti-IgE and specific allergens was evaluated. It was shown that both allergenic extracts, Catalet C and Catalet D, are really immunogenic, which is manifested in a decrease in specific IgE and in a marked increase in specific IgG4, after 2 years of sIT. In comparison with the placebo, the sensitivity of blood basophils to both specific allergens and non-specific factors significantly decreased.
在一组41名对杂草或树木花粉过敏的花粉症和/或季节性哮喘患者中，评估了特异性免疫疗法（sIT）对IgE、特异性IgE和IgG4水平以及抗IgE和特异性变应原诱导的组胺释放（HR）的影响。结果表明，两种变应原提取物Catalet C和Catalet D确实具有免疫原性，这表现为经过2年的sIT后，特异性IgE降低，特异性IgG4显著增加。与安慰剂相比，血液嗜碱性粒细胞对特异性变应原和非特异性因素的敏感性显著降低。
