Noël L
Etablissement de Transfusion Sanguine de l'Ouest Francilien, Versailles.
Transfus Clin Biol. 1996;3(1):35-42. doi: 10.1016/s1246-7820(96)80011-5.
Transfusion associated bacterial sepsis, TABS, may be caused by-donor bacteremia,-bacteria from the donors skin,-bacteria brought by one of the persons handling the donation or the blood product, from collection and components preparation to the actual transfusion,-or bacteria introduced by a defect in one of the disposables used. Quality Assurance relies on the Good Transfusion Practices of the French Blood Agency all along the transfusion chain from the donor to the recipient. Active involvement of personnel, standardisation and controls as well as improvement of technics particularly as regarding donor selection, skin disinfection technics and collection are required. The ultimate control is hemovigilance with proper identification and investigation of all cases of TABS even with mild symptoms. Centralisation of data in the Haemovigilance scheme is a further step toward a better understanding and improvement of blood products bacterial security.
输血相关细菌性败血症(TABS)可能由以下原因引起:供体菌血症、来自供体皮肤的细菌、参与献血或血液制品处理(从采集和成分制备到实际输血)的人员所携带的细菌,或一次性用品的缺陷引入的细菌。质量保证依赖于法国血液机构在从供体到受者的整个输血链中的良好输血实践。需要人员的积极参与、标准化和控制以及技术改进,特别是在供体选择、皮肤消毒技术和采集方面。最终的控制是血液警戒,对所有TABS病例进行适当识别和调查,即使是症状轻微的病例。将数据集中在血液警戒计划中是朝着更好地理解和改善血液制品细菌安全性迈出的又一步。