Troulis M J, Head T W, Leclerc J R
Oral and Maxillofacial Surgery Program at McGill University.
J Can Dent Assoc. 1996 May;62(5):428-30.
The World Health Organization (WHO), the International Committee for Thrombosis and Hemostasis, and the International Committee for Standardization in Hematology, have strongly suggested that INR (International Normalized Ratio) values should be used to report a patient's level of coagulation. This paper discusses the use of the INR to monitor a patient's coagulation level, and reviews the recommendations on the INR levels at which dental extractions and similar oral surgical procedures may be performed safely. Studies are needed to determine whether new local hemostatic agents are sufficient for the safe management of patients at higher INR levels, thereby avoiding the need for hospitalization and heparin therapy.
世界卫生组织（WHO）、国际血栓形成与止血委员会以及国际血液学标准化委员会强烈建议，应使用国际标准化比值（INR）来报告患者的凝血水平。本文讨论了使用INR监测患者凝血水平的情况，并回顾了关于在何种INR水平下可安全进行拔牙及类似口腔外科手术的建议。需要开展研究以确定新型局部止血剂对于INR水平较高患者的安全管理是否足够，从而避免住院治疗和肝素治疗的必要性。
