Kokmen E, Bossemeyer R W, Barney J, Williams W J
J Gerontol. 1977 Jul;32(4):411-9. doi: 10.1093/geronj/32.4.411.
A group of 51 socially active, self-declared neurologically normal subjects ranging from 61 to 84 years of age were studied with a battery of clinical neurological examinations and a semiquantitative vibration perception test. None of the subjects showed a consistent pattern of neurological deficit that could be identified as pathological. On review of systems, the most frequent complaints were difficulty remembering names, numbness and tingling of fingers and toes, and headaches. In the neurological examination, the most commonly observed abnormalities were positive palmomental reflex, snout reflex, abnormalities in pursuit eye movements, convergence insufficiency, and minor mistakes in perception of light touch. There was no apparent trend of worsening of symptoms and signs with advancing age. In the semiquantitative testing of vibration perception, there was a slight trend toward worsening of vibration perception in the upper and lower extremities with advancing age. Motor abnormalities were absent, and there were relatively few subjects who showed reflex abnormalities. This study confirms the previously reported diminution of vibration perception with aging. Caution must be exercised before attributing myotatic reflex and motor abnormalities to the aging process alone.
对一组年龄在61岁至84岁之间、社交活跃且自称神经系统正常的51名受试者进行了一系列临床神经学检查和半定量振动觉测试。没有一名受试者表现出可被认定为病理性的一致神经功能缺损模式。在系统回顾中，最常见的主诉是记名字困难、手指和脚趾麻木及刺痛，以及头痛。在神经学检查中，最常观察到的异常是掌颏反射阳性、噘嘴反射、追踪眼球运动异常、集合不足以及轻触觉感知的轻微错误。症状和体征没有随年龄增长而明显恶化的趋势。在振动觉的半定量测试中，随着年龄增长，上肢和下肢的振动觉有轻微恶化趋势。未发现运动异常，且表现出反射异常的受试者相对较少。本研究证实了先前报道的随着年龄增长振动觉减退。在仅将肌伸张反射和运动异常归因于衰老过程之前必须谨慎。
