Grevelink S A, Lerner E A
Department of Dermatology, Harvard Medical School, Boston, Massachusetts, USA.
J Am Acad Dermatol. 1996 Feb;34(2 Pt 1):257-72. doi: 10.1016/s0190-9622(96)80121-6.
Leishmaniasis is a protozoan disease whose diverse clinical manifestations are dependent both on the infecting species of Leishmania and on the immune response of the host. Transmission of the disease occurs through the bite of a sand fly infected with Leishmania parasites. Infection may be restricted to the skin in cutaneous leishmaniasis, limited to the mucous membranes in mucosal leishmaniasis, or spread throughout the reticuloendothelial system in visceral leishmaniasis or kala azar. Three rare clinical variants of cutaneous leishmaniasis include diffuse cutaneous leishmaniasis, leishmaniasis recidivans, and post-kala-azar dermal leishmaniasis.
利什曼病是一种原生动物疾病，其多样的临床表现既取决于感染的利什曼原虫种类，也取决于宿主的免疫反应。该疾病通过感染利什曼原虫寄生虫的白蛉叮咬传播。在皮肤利什曼病中，感染可能局限于皮肤；在黏膜利什曼病中，感染局限于黏膜；在内脏利什曼病或黑热病中，感染则会扩散至整个网状内皮系统。皮肤利什曼病的三种罕见临床变体包括弥漫性皮肤利什曼病、复发性利什曼病和黑热病后皮肤利什曼病。
