膳食抗氧化剂预防动脉粥样硬化：事实还是虚构？
Prevention of atherosclerosis with dietary antioxidants: fact or fiction?
作者信息
Duell P B
机构信息
Division of Endocrinology, Diabetes and Nutrition, Oregon Health Sciences University, Portland, OR 97201-3098, USA.
出版信息
J Nutr. 1996 Apr;126(4 Suppl):1067S-71S. doi: 10.1093/jn/126.suppl_4.1067S.
The notion that oxidation of lipids and lipoproteins may contribute to the pathogenesis of atherosclerosis is supported by a large body of evidence. It is hypothesized that dietary antioxidants may help prevent development and progression of atherosclerosis. The available evidence helps substantiate this hypothesis but is not yet conclusive. The results of several ongoing large randomized intervention trials will provide valuable information about the efficacy and safety of supplemental dietary antioxidants in prevention of atherosclerosis.
大量证据支持脂质和脂蛋白氧化可能促成动脉粥样硬化发病机制的观点。据推测，膳食抗氧化剂可能有助于预防动脉粥样硬化的发生和发展。现有证据有助于证实这一假说，但尚未得出定论。几项正在进行的大型随机干预试验的结果将为补充膳食抗氧化剂预防动脉粥样硬化的有效性和安全性提供有价值的信息。
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