Mwangi D M, Hopkins J, Luckins A G
Centre for Tropical Veterinary Medicine, University of Edinburgh, UK.
Vet Parasitol. 1995 Nov;60(1-2):45-52. doi: 10.1016/0304-4017(94)00752-x.
Events occurring in the skin of sheep prior to development of Trypanosoma congolense-induced local skin reactions (chancres) were studied using electron microscopy. Three days after infection, few trypanosomes were present in the dermal collagen. However, these parasites were more abundant 5 days after infection, and were also found in dermal lymphatics and in the connective tissue matrix between collagen bundles. Mast cells in the skin obtained 5 days after infection showed evidence of degranulation. These events may play a role during the induction phase of trypanosomal chancres.
利用电子显微镜研究了绵羊在感染刚果锥虫引起局部皮肤反应（溃疡）之前皮肤中发生的事件。感染后三天，真皮胶原中存在少量锥虫。然而，这些寄生虫在感染后5天更为丰富，并且也在真皮淋巴管以及胶原束之间的结缔组织基质中被发现。感染后5天获取的皮肤中的肥大细胞显示出脱颗粒的迹象。这些事件可能在锥虫性溃疡的诱导阶段发挥作用。
