Martín-Vivaldi Martínez R, Espinosa Aguilar M D, Sánchez Sanchéz-Vizcaíno J, Quintero Fuentes D, Nogueras López F, López de Hierro Ruiz M
Servicio de Aparato Digestivo, Hospital Virgen de las Nieves, Granada.
Rev Esp Enferm Dig. 1996 Mar;88(3):213-6.
Porphyria cutanea tarda (PCT) is caused by reduced activity of hepatic uroporphyrinogen decarboxylase. However extrinsic factors such as alcohol abuse and drug intake are required for the clinical manifestation of the disease. Hepatitis C virus antibodies have been detected in a high percentage of patients with PCT. Hepatitis C virus is probably the main pathogenetic factor of liver damage in patients with PCT.
To study the association between hepatitis C virus and PCT in our patients with PCT.
We have investigated six patients diagnosed of PCT in order to detect the presence of hepatitis C virus and other possible causes of the disease.
We have found that 66% of our patients had hepatitis C virus antibodies, 50% ethanol abuse, of which 2/3 presented hepatitis C virus antibodies, and one case of HIV.
迟发性皮肤卟啉病（PCT）由肝脏尿卟啉原脱羧酶活性降低引起。然而，诸如酗酒和药物摄入等外部因素是该疾病临床表现所必需的。在高比例的PCT患者中检测到丙型肝炎病毒抗体。丙型肝炎病毒可能是PCT患者肝脏损伤的主要致病因素。
研究丙型肝炎病毒与我们的PCT患者中PCT之间的关联。
我们调查了6例诊断为PCT的患者，以检测丙型肝炎病毒的存在及该疾病的其他可能病因。
我们发现66%的患者有丙型肝炎病毒抗体，50%有酗酒，其中2/3有丙型肝炎病毒抗体，还有1例感染HIV。
