Olsson J, Berglund L, Hahn R G
Sundsvall Central Hospital, Sweden.
Br J Obstet Gynaecol. 1996 Jun;103(6):558-61. doi: 10.1111/j.1471-0528.1996.tb09806.x.
Absorption of irrigating fluid may occur through severed blood vessels during endometrial resection. We studied whether irrigating fluid can also be absorbed through the undamaged uterus.
We studied 25 women, aged 28-46 years (mean 38 years), who underwent elective laparoscopic sterilisation under general anaesthesia.
In 15 women blue-stained irrigating fluid containing glycine 1.5% and ethanol 1% was applied to the uterine cavity under increasing pressure. Laparoscopy was employed to see when fluid emerged from the Fallopian tubes. Another 10 women had their Fallopian tubes clamped before the fluid pressure was raised, and systemic absorption was detected by measuring the serum glycine concentration.
Passage of fluid through the Fallopian tubes occurred in 14 of the 15 patients at a uteroabdominal pressure gradient of 40 mmHg (n = 4), 80 mmHg (n = 4), 120 mmHg (n = 3), and 160 mmHg (n = 3), respectively. The fluid passage rate ranged between 0.5 and 13 (mean 6.4) ml min-1. Of the women with clamped Fallopian tubes, 8 of 10 showed an increase in the serum glycine level of 60% at a pressure gradient of 160 mmHg, and of 120% at 200 mmHg.
Uterotubal and transendometrial passage of small to moderate amounts of irrigating solution occurred frequently at the intrauterine fluid pressures normally used during endometrial resection.
子宫内膜切除术中，冲洗液可能通过切断的血管被吸收。我们研究了冲洗液是否也能通过未受损的子宫被吸收。
我们研究了25名年龄在28 - 46岁（平均38岁）的女性，她们在全身麻醉下接受了择期腹腔镜绝育术。
15名女性中，在逐渐增加的压力下，将含有1.5%甘氨酸和1%乙醇的蓝色染色冲洗液注入子宫腔。采用腹腔镜观察液体何时从输卵管流出。另外10名女性在提高液体压力前夹住输卵管，并通过测量血清甘氨酸浓度检测全身吸收情况。
15名患者中有14名在子宫腹压差为40 mmHg（n = 4）、80 mmHg（n = 4）、120 mmHg（n = 3）和160 mmHg（n = 3）时，液体通过输卵管。液体通过率在0.5至13（平均6.4）ml·min⁻¹之间。在夹住输卵管的女性中，10名中有8名在压力梯度为160 mmHg时血清甘氨酸水平升高60%，在200 mmHg时升高120%。
在子宫内膜切除术中通常使用的子宫内液体压力下，中小量冲洗液频繁地通过子宫输卵管和经子宫内膜通道。
