Penfold C N, Partridge M, Rojas R, Langdon J D
Maxillofacial Unit, Queen Victoria Hospital NHS Trust, East Grinstead, London.
Br J Oral Maxillofac Surg. 1996 Feb;34(1):37-41. doi: 10.1016/s0266-4356(96)90133-3.
Microvessels were counted in 41 primary oral squamous cell carcinomas using JC70 antibody to PECAM (CD31). The counts were compared with clinical and pathological indicators of tumour behaviour including lymph node status, tumour stage, type of histological differentiation, size and velocity of tumour growth. Tumour microvessel counts correlated with lymph node metastasis (p < 0.001). This association was independent of tumour size, velocity and type of histological differentiation and when all the variables were analysed by multivariate analysis only vascular count showed a significant association with lymph node metastasis.
使用针对PECAM（CD31）的JC70抗体，对41例原发性口腔鳞状细胞癌中的微血管进行计数。将计数结果与肿瘤行为的临床和病理指标进行比较，这些指标包括淋巴结状态、肿瘤分期、组织学分化类型、肿瘤大小和生长速度。肿瘤微血管计数与淋巴结转移相关（p < 0.001）。这种关联独立于肿瘤大小、生长速度和组织学分化类型，并且当通过多变量分析对所有变量进行分析时，只有血管计数显示与淋巴结转移存在显著关联。
