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Peripheral blood gamma delta T cells in human listeriosis.

作者信息

Bertotto A, Spinozzi F, Gerli R, Bassotti G, Forenza N, Vagliasindi C, Vaccaro R

机构信息

Department of Paediatrics, Perugia University Medical School, Italy.

出版信息

Acta Paediatr. 1995 Dec;84(12):1434-5. doi: 10.1111/j.1651-2227.1995.tb13584.x.

DOI:10.1111/j.1651-2227.1995.tb13584.x
PMID:8645966
Abstract

A phenotypical analysis carried out by direct immunofluorescence and two-colour cytofluorometry showed that the number of lymphocytes bearing the gamma delta T-cell receptor heterodimer was increased in the blood of eight children with Listeria monocytogenes infection, mainly due to an expansion of cells identified by monoclonal antibodies which recognize V delta 2 gene products. These findings are further evidence that gamma delta T cells are in some way involved in the immune response directed against human intracellular pathogens.

摘要

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