Gürpinar T, Griffith D P
Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030, USA.
World J Urol. 1996;14(1):47-52. doi: 10.1007/BF01836344.
Bladder reconstruction may be required in a variety of pathological conditions, including bladder cancer, irradiation cystitis, interstitial cystitis, tuberculosis, and various congenital anomalies. Currently, bladder reconstruction is done with an autogenous bowel segment. Use of a total prosthetic bladder as an intracorporeal urinary reservoir has been an elusive goal for many decades. Many investigational and a few clinical trials have been performed in an attempt to develop a near-normal bladder prosthesis utilizing alloplastic materials. To date the ideal prosthetic bladder has not been developed. However, cumulative experimental studies suggest that many, perhaps all, of the ideal functional characteristics of a total prosthetic bladder are possible. Basically, two different alloplastic models have been investigated.
在多种病理情况下可能需要进行膀胱重建，包括膀胱癌、放射性膀胱炎、间质性膀胱炎、结核病以及各种先天性异常。目前，膀胱重建是使用自体肠段进行的。几十年来，将全人工膀胱用作体内储尿器一直是一个难以实现的目标。为了开发一种利用异体材料的接近正常的膀胱假体，已经进行了许多研究性试验和一些临床试验。迄今为止，理想的人工膀胱尚未研制出来。然而，累积的实验研究表明，全人工膀胱的许多甚至可能所有理想功能特性都是有可能实现的。基本上，已经研究了两种不同的异体材料模型。
