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头孢呋辛在创伤性脑损伤患者脑脊液中的渗透情况。

Penetration of cefuroxime into the cerebrospinal fluid of patients with traumatic brain injury.

作者信息

Kossmann T, Hans V, Stocker R, Imhof H G, Joos B, Trentz O, Morganti-Kossmann M C

机构信息

Department of Surgery, University of Zürich, Medical School, Switzerland.

出版信息

J Antimicrob Chemother. 1996 Jan;37(1):161-7. doi: 10.1093/jac/37.1.161.

DOI:10.1093/jac/37.1.161
PMID:8647759
Abstract

Cefuroxime levels were measured in cerebrospinal fluid (CSF) and serum of four patients with traumatic brain injury following the implantation of intraventricular catheters. The levels ranged from 0.15 to 2.03 micrograms/mL in CSF and from 1.8 to 66.9 micrograms/mL in serum. No ventriculostomy related infections were detected.

摘要

对4例脑外伤患者在植入脑室内导管后，测定其脑脊液（CSF）和血清中的头孢呋辛水平。脑脊液中的水平范围为0.15至2.03微克/毫升，血清中的水平范围为1.8至66.9微克/毫升。未检测到与脑室造瘘相关的感染。

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