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灭活的牛疱疹病毒1诱导丝裂原刺激的牛外周血单个核细胞发生凋亡性细胞死亡。

Inactivated bovine herpesvirus 1 induces apoptotic cell death of mitogen-stimulated bovine peripheral blood mononuclear cells.

作者信息

Hanon E, Vanderplasschen A, Lyaku S, Keil G, Denis M, Pastoret P P

机构信息

Department of Immunology/Vaccinology, Faculty of Veterinary Medicine, University of Liège, Belgium.

出版信息

J Virol. 1996 Jun;70(6):4116-20. doi: 10.1128/JVI.70.6.4116-4120.1996.

Abstract

Bovine herpesvirus 1 (BHV-1) is able to inhibit the proliferation of bovine peripheral blood mononuclear cells. Here, we have demonstrated that live BHV-1 and, interestingly, inactivated BHV-1 can induce apoptosis of mitogen-stimulated bovine peripheral blood mononuclear cells in vitro.

摘要

牛疱疹病毒1型(BHV - 1)能够抑制牛外周血单个核细胞的增殖。在此,我们已经证明,活的BHV - 1,有趣的是,灭活的BHV - 1在体外能够诱导丝裂原刺激的牛外周血单个核细胞凋亡。

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本文引用的文献

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Activation-induced apoptosis in lymphocytes.淋巴细胞中激活诱导的凋亡
Curr Opin Immunol. 1994 Jun;6(3):476-87. doi: 10.1016/0952-7915(94)90130-9.
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Apoptosis in viral infections.病毒感染中的细胞凋亡
Adv Virus Res. 1995;45:1-60. doi: 10.1016/s0065-3527(08)60057-3.

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