Riabov S I, Stavskaia V V
Klin Med (Mosk). 1996;74(1):17-20.
Clinical course of chronic glomerulonephritis (CG) with recognition of 4 types by frequency of exacerbations was investigated in 592 patients with morphologically verified diagnosis observed for a long time. The disease ran a stable course. Contrary to patients with mesangioproliferative CG who had rare or moderate-frequency exacerbations, patients with membranoproliferative disease had exacerbations annually. This suggests correlation between the form of anatomical changes and the process activity. Irrespective of CG morphological form, the survival of CG patients is closely related to the disease course. Taken into account, this fact may serve the tool of prognosis, choice of treatment intensity and duration of follow-up.
对592例经长期观察且形态学诊断得到证实的慢性肾小球肾炎(CG)患者进行了研究,根据病情加重频率识别出4种类型。该疾病呈稳定病程。与系膜增生性CG患者(病情加重罕见或频率适中)相反,膜增生性疾病患者每年都会病情加重。这表明解剖学改变形式与疾病进程活动之间存在相关性。无论CG的形态学类型如何,CG患者的生存率与病程密切相关。考虑到这一事实,其可作为预后工具、治疗强度选择及随访持续时间的依据。