Bosan-Kilibarda I, Rumenjak V, Ciprić M, Macan D
Ustanova za hitnu medicinsku pomoć Zagreb.
Lijec Vjesn. 1995 Jun;117 Suppl 2:109-11.
The present study has been undertaken to compare the Q.E.D. test, a quantitative enzymatic method for the determination of ethanol concentration in the saliva, and quantitative methods for determination of ethanol serum concentrations: UV alcohol dehydrogenase method and gas chromatography. The results of the study demonstrated a statistically significant correlation between the methods compared. We conclude that Q.E.D. test is an effective, rapid and safe method for specific quantitative determination of ethanol levels in the blood defined by ethanol concentrations in the saliva, especially in outpatient departments, initial emergency treatment as well as in differential diagnosis. Sometimes, an increased salivary viscosity caused by dehydration of an acutely drunken man as well as insufficient cooperation of the examinee may, however, aggravate the test performance. We propose the use of a test that measures ethanol concentration in the saliva up to 3.5 g/L in order to avoid repetition of the test.
本研究旨在比较Q.E.D.检测法(一种用于测定唾液中乙醇浓度的定量酶法)与测定血清乙醇浓度的定量方法:紫外酒精脱氢酶法和气相色谱法。研究结果表明,所比较的方法之间存在统计学上的显著相关性。我们得出结论,Q.E.D.检测法是一种有效、快速且安全的方法,可根据唾液中的乙醇浓度特异性定量测定血液中的乙醇水平,尤其适用于门诊、初始急诊治疗以及鉴别诊断。然而,急性醉酒者脱水导致唾液粘度增加以及受检者配合度不足有时可能会影响检测结果。为避免重复检测,我们建议使用一种可测量唾液中乙醇浓度高达3.5 g/L的检测方法。