Ihász M, Regöly-Mérei J, Szeberin Z, Bátorfi J, Fazekas T, Máté M
Orv Hetil. 1996 May 5;137(18):955-63.
The authors analyse the etiology, diagnosis, treatment and outcome of 148 biliary tract injuries in connection with 26,440 laparoscopic cholecystectomies performed in 89 domestic institutes between January 1st, 1991, and December 31st, 1994. There was no significant correlation between the amount of laparoscopic cholecystectomies performed in one institute and the incidence of biliary tract injuries and postoperative bile leakage (wide range of figures were found in different institutes), but in the second year of practice, the incidence of both complication decreased (there was statistically significant difference between the regression co-efficients). There was no significant correlation between the laparoscopic cholecystectomies performed and the rate of conversion, but the co-efficient of the regression curve showing the correlation of the absolute number of laparoscopic cholecystectomies and conversions significantly decreased in the second year of practice. In institutes having significantly more conversions, more cases of bile leakage was found also. There is a significantly positive relationship between biliary tract injuries and postoperative bile leakage; the more lesions are found in an institute, the more cases of bile leakage they have. There was no significant relationship between the incidence biliary tract injuries and postoperative bile leakage and the usage of intraoperative cholangiography, preoperative intravenous cholangiography and/or ERCP. The partial and complete injuries of main bile ducts were detected intraoperatively significantly more often while most of the lesions of the area of cystic duct were detected postoperatively. There was no significant difference between the types of the only postoperative recognized injuries and the time of establishing the diagnosis. Simple suture was performed in 69.2% of the partial injuries (with or without T-tube or other drainage), while 63.3% of the complete transsections were treated with biliodigestive anastomosis. In univariant analysis the type of injury, the primary treatment modality did not affect on the outcome (the ratio of cured and expired), but significantly more patients continue to have complaints following biliodigestive anastomosis than following the treatment of lesions around the cystic duct. The older the patient is, the worse the prognosis is. The primary treatment modality (biliodigestive anastomosis or biliary tract reconstruction with or without drain) did not significantly altered the necessity of reoperation. Thermic injury caused significantly more partial than complete lesion. Disturbance in identification of the anatomic structures leads significantly more partial or complete main bile duct injuries than lesion in region of the cystic duct and causes more complete transsections than partial lesions. According to multivariant analysis the outcome is significantly influenced in an adverse way by the necessity of repeated interventions and higher age.
作者分析了1991年1月1日至1994年12月31日期间,国内89家机构进行的26440例腹腔镜胆囊切除术相关的148例胆道损伤的病因、诊断、治疗及预后。各机构进行的腹腔镜胆囊切除术数量与胆道损伤及术后胆漏发生率之间无显著相关性(不同机构的数据差异很大),但在实践的第二年,两种并发症的发生率均有所下降(回归系数有统计学显著差异)。腹腔镜胆囊切除术的实施与中转率之间无显著相关性,但显示腹腔镜胆囊切除术绝对数量与中转率相关性的回归曲线系数在实践的第二年显著下降。在中转率明显更高的机构中,胆漏病例也更多。胆道损伤与术后胆漏之间存在显著正相关;一个机构发现的损伤越多,其胆漏病例就越多。胆道损伤及术后胆漏的发生率与术中胆管造影、术前静脉胆管造影和/或内镜逆行胰胆管造影(ERCP)的使用之间无显著关系。主胆管的部分和完全损伤在术中被检测到的频率明显更高,而胆囊管区域的大多数损伤在术后被检测到。仅术后才被识别的损伤类型与诊断确立时间之间无显著差异。69.2%的部分损伤采用了单纯缝合(有或无T管或其他引流),而63.3%的完全横断伤采用了胆肠吻合术治疗。在单因素分析中,损伤类型、初始治疗方式对预后(治愈和死亡比例)无影响,但与胆囊管周围病变治疗相比,胆肠吻合术后仍有明显更多患者持续存在不适。患者年龄越大,预后越差。初始治疗方式(胆肠吻合术或有或无引流的胆道重建)并未显著改变再次手术的必要性。热损伤导致的部分损伤明显多于完全损伤。解剖结构识别障碍导致的主胆管部分或完全损伤明显多于胆囊管区域的损伤,且导致的完全横断伤多于部分损伤。根据多因素分析,重复干预的必要性和较高年龄对预后有显著不利影响。