Tanière P, Poulard G, Frappart L, Berger G, Goncalves M, Vauzelle J L, Delecluse D J, Bailly C, Boucheron S, Berger F
Laboratoire central d'Anatomie Pathologique, Hôpital Edouard Herriot, Lyon.
Ann Pathol. 1996;16(1):33-6.
Two cases of diabetic mastopathy are reported. The patients presented with a rapidly increasing mammary mass. The pathologic findings of diabetic mastopathy usually consist of a lymphocytic lobulitis, a dense stromal fibrosis and prominent epithelioid fibroblasts. In our two cases, the latter findings were initially misinterpreted as malignant cells of an invasive lobular carcinoma. These lesions were first described in longstanding insulin dependent diabetics but recent reports showed that they could also occur in patients with other auto-immune disorders (systemic lupus erythematous, hypothyroidism). Diabetic mastopathy may reoccur locally and the treatment remains to be determined.
报告了两例糖尿病性乳腺病。患者表现为乳腺肿块迅速增大。糖尿病性乳腺病的病理表现通常包括淋巴细胞性小叶炎、致密的间质纤维化和显著的上皮样成纤维细胞。在我们的两例病例中，后一种表现最初被误诊为浸润性小叶癌的恶性细胞。这些病变最初在长期胰岛素依赖型糖尿病患者中被描述，但最近的报告显示，它们也可能发生在其他自身免疫性疾病（系统性红斑狼疮、甲状腺功能减退症）患者中。糖尿病性乳腺病可能会局部复发，治疗方法仍有待确定。
