Lieb W E, Maurer J, Müller-Forell W, Mann W
Augenklinik, Johannes-Gutenberg-Universität, Mainz.
Ophthalmologe. 1996 Apr;93(2):194-8.
The therapy of traumatic optic neuropathy remains controversial. Some authors recommend observation and others, the use of megadose corticosteroids or surgical decompression of the optic nerve. Improvements in visual acuity from no light perception (NLP) preoperatively to close to normal visual acuities have been reported after transethmoidal decompression and systemic steroids. The transnasal microscopic approach offers safe and effective access to the optic canal.
Retrospectively 15 patients (13 men/2 women) ranging in age from 17 to 67 years, who were surgically decompressed in the Ear-Nose-Throat Department between 1989 and 1994, were analyzed. Thirteen patients had experienced sudden visual loss after trauma; in 2 patients a tumor was diagnosed. After an initial ophthalmologic examination and CT scans, the patients underwent transnasal decompression of the optic canal for at least 180 degrees. In the postoperative period, visual acuity, pupillary reaction, visual field and optic nerve morphology were monitored.
The overall visual results were poor. In 8 patients with no light perception (NLP) preoperatively, no improvement in visual acuity was found. Minor improvements were seen with an initial vision of 20/200 or less. Dramatic improvements were found in both patients with rapidly progressive neoplastic optic nerve compression. No intra- or postoperative complications were seen.
In our study we were unable to reproduce the good visual results of some series. If there is NLP preoperatively, surgical intervention does not seem to be promising. However, in patients with incurable tumors transnasal decompression of the optic canal offers a minimally invasive palliative measure to preserve and restore vision.
外伤性视神经病变的治疗仍存在争议。一些作者建议观察,另一些作者则建议使用大剂量皮质类固醇或对视神经进行手术减压。经筛窦减压和全身使用类固醇后,有报告称视力从术前无光感提高到接近正常视力。经鼻显微镜手术入路能安全有效地进入视神经管。
回顾性分析了1989年至1994年间在耳鼻喉科接受手术减压的15例患者(13例男性/2例女性),年龄在17至67岁之间。13例患者外伤后突然视力丧失;2例患者被诊断为肿瘤。经过初步眼科检查和CT扫描后,患者接受了至少180度的经鼻视神经管减压术。术后监测视力、瞳孔反应、视野和视神经形态。
总体视觉效果较差。术前无光感的8例患者视力无改善。初始视力为20/200或更低的患者有轻微改善。2例快速进展性肿瘤性视神经压迫患者视力有显著改善。未观察到术中或术后并发症。
在我们的研究中,我们无法重现一些系列研究中的良好视觉效果。如果术前无光感,手术干预似乎没有希望。然而,对于无法治愈的肿瘤患者,经鼻视神经管减压术提供了一种微创姑息措施,以保留和恢复视力。