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鼻内镜下外伤性失明挽救性视神经减压术:风险与效益分析

Salvage optic nerve decompression for traumatic blindness under nasal endoscopy: risk and benefit analysis.

作者信息

Li H B, Shi J B, Cheng L, Yun O, Xu G

机构信息

Department of Otolaryngology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

出版信息

Clin Otolaryngol. 2007 Dec;32(6):447-51. doi: 10.1111/j.1749-4486.2007.01560.x.

DOI:10.1111/j.1749-4486.2007.01560.x
PMID:18076430
Abstract

OBJECTIVES

Transnasal endoscopic optic nerve decompression was recommended to treat traumatic optic neuropathy as an effectively adjunctive procedure. The aim of this study was to assess the risks and benefits of salvage surgical decompression for complete vision loss (no light detection) after failure of mega-dose steroid therapy.

DESIGN

Retrospective study.

SETTING

Two hospitals in Guangzhou and Nanjing, China.

PARTICIPANTS

Forty-two patients of traumatic optic neuropathy with complete vision loss and failed to improve after steroid therapy for at least 3 days.

MAIN OUTCOME MEASURES

All patients were treated by transnasal endoscopic optic nerve decompression and received follow-up for at least 6 month. Vision improvement and complications were evaluated.

RESULTS

Transnasal endoscopic optic nerve decompression was performed successfully in 40 patients and was incomplete in two patients due to bleeding. Vision improved in four of 42 patients (9.5%) of traumatic optic neuropathy with complete vision loss and failed steroid therapy. Complications and sequelae included severe bleeding (two cases), cerebrospinal fluid rhinorrhea (one case), nasal polyps (seven cases), chronic sinusitis (four cases) and nasal synechia (17 cases).

CONCLUSION

Transnasal endoscopic optic nerve decompression was recommended as a minimally invasive, safe procedure, but complications and sequelae of the surgery should not be neglected. Based on the risk and benefit analysis, we conclude that the very poor surgical outcomes of this series do not support endoscopic optic nerve decompression for traumatic blindness.

摘要

目的

经鼻内镜视神经减压术被推荐作为治疗创伤性视神经病变的一种有效辅助手术。本研究的目的是评估在大剂量类固醇治疗失败后,挽救性手术减压治疗完全视力丧失(无光感)的风险和益处。

设计

回顾性研究。

地点

中国广州和南京的两家医院。

参与者

42例创伤性视神经病变患者,视力完全丧失,且在类固醇治疗至少3天后未改善。

主要观察指标

所有患者均接受经鼻内镜视神经减压术治疗,并至少随访6个月。评估视力改善情况和并发症。

结果

40例患者经鼻内镜视神经减压术成功,2例因出血手术未完成。42例视力完全丧失且类固醇治疗失败的创伤性视神经病变患者中,4例(9.5%)视力改善。并发症和后遗症包括严重出血(2例)、脑脊液鼻漏(1例)、鼻息肉(7例)、慢性鼻窦炎(4例)和鼻腔粘连(17例)。

结论

经鼻内镜视神经减压术被推荐为一种微创、安全的手术,但手术的并发症和后遗症不应被忽视。基于风险和效益分析,我们得出结论,本系列手术效果极差,不支持内镜下视神经减压术治疗外伤性失明。

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