Johnson W K, Stoupis C, Torres G M, Rosenberg E B, Ros P R
Department of Radiology, University of Florida College of Medicine, Gainesville 32610-0374, USA.
Magn Reson Imaging. 1996;14(1):43-9. doi: 10.1016/0730-725x(95)02044-t.
This study was conducted to compare the sensitivity and specificity of abdominal magnetic resonance imaging using oral superparamagnetic iron oxide with oral contrast-enhanced computed tomography in the detection of GI pathology. Overall sensitivity was calculated to be 83% for OECT compared to 67% by SPIO MRI. Specificity for OECT was 68% compared to 89% for SPIO MRI. The results from imaging with superparamagnetic iron oxide and imaging with oral contrast-enhanced computed tomography were in agreement in 14 subjects who had normal gastrointestinal tracts. In the remaining 16 patients, eight pathologic entities were detected by both modalities whereas 15 abnormalities were seen by only one modality. Superparamagnetic iron oxide magnetic resonance imaging was helpful in discriminating normal bowel from solid lesions and in detecting subtle gastrointestinal tract mass effect. In 30 consecutively studied patients suspected of having GI pathology, OECT was more sensitive than SPIO MRI in detecting abdominal pathology. Conversely, SPIO MRI was more specific than OECT.
本研究旨在比较口服超顺磁性氧化铁的腹部磁共振成像与口服对比增强计算机断层扫描在检测胃肠道病变方面的敏感性和特异性。计算得出，口服对比增强计算机断层扫描（OECT）的总体敏感性为83%，而超顺磁性氧化铁磁共振成像（SPIO MRI）为67%。OECT的特异性为68%，而SPIO MRI为89%。14名胃肠道正常的受试者中，超顺磁性氧化铁成像和口服对比增强计算机断层扫描成像的结果一致。在其余16名患者中，两种检查方式均检测到8种病理实体，而仅一种检查方式发现15处异常。超顺磁性氧化铁磁共振成像有助于区分正常肠管与实性病变，并检测细微的胃肠道肿块效应。在连续研究的30名怀疑有胃肠道病变的患者中，OECT在检测腹部病变方面比SPIO MRI更敏感。相反，SPIO MRI比OECT更具特异性。
