不同的热休克蛋白在适应镉和五氯苯酚的纤细裸藻细胞中组成性过表达。

Different heat-shock proteins are constitutively overexpressed in cadmium and pentachlorophenol adapted Euglena gracilis cells.

作者信息

Barque J P, Abahamid A, Chacun H, Bonaly J

机构信息

Laboratoire Métabolisme Cellulaire et Xénobiotiques, Faculté de Pharmacie, Châtenay-Malabry, France.

出版信息

Biochem Biophys Res Commun. 1996 Jun 5;223(1):7-11. doi: 10.1006/bbrc.1996.0837.

DOI:10.1006/bbrc.1996.0837

PMID:8660381

Abstract

To determine whether cellular resistance to a given stressor is related to induction of specific stress-proteins, responses of two adapted Euglena gracilis cell lines, one adapted to cadmium, the other adapted to pentachlorophenol, were analyzed. Our experiments showed that two sets of heat-shock proteins (hsps) were constitutively overexpressed in each cell line: while hsp90, hsp70, hsp55, and hsp40 were induced in cadmium-resistant cells, only hsp40 was induced in pentachlorophenol-adapted cells.

摘要

为了确定细胞对特定应激源的抗性是否与特定应激蛋白的诱导有关，分析了两种适应环境的纤细裸藻细胞系的反应，一种适应镉，另一种适应五氯苯酚。我们的实验表明，每组热休克蛋白（hsps）在每个细胞系中都组成性过表达：在抗镉细胞中诱导出hsp90、hsp70、hsp55和hsp40，而在适应五氯苯酚的细胞中仅诱导出hsp40。