Thorne R, Foreman N K, Mott M G
Department of Paediatric Oncology, Royal Hospital for Sick Children, Bristol, U.K.
Eur J Cancer. 1996 Feb;32A(2):282-5. doi: 10.1016/0959-8049(95)00523-4.
Exposure to radon in dwellings may cause cancer including paediatric malignancies. Devon and Cornwall have the highest exposure to radon of the counties of England. However, within these counties there is considerable variation in exposure. Exposure to radon in the 283 postcode sectors of the two counties has been published. The incidence of childhood malignancies between 1976 and 1985 was studied to compare postcode sectors of radon exposures > or = 100 Bq/m3 with sectors < 100 Bq/m3. No significant difference in the incidence rate of 106.7 per million child years in the high radon postcode sectors and 121.7 in the low (P = 0.29) was found. When the incidences of individual tumours were examined, a significantly increased rate of neuroblastoma (P = 0.02) and a non-significant increased rate of acute myeloid leukaemia were found in the high exposure postcode sectors. No association between radon exposure and overall rate of childhood malignancy was found.
居住环境中接触氡气可能会引发癌症，包括儿童恶性肿瘤。在英格兰各郡中，德文郡和康沃尔郡的氡气接触量最高。然而，在这些郡内，接触量存在很大差异。这两个郡283个邮政编码区域的氡气接触情况已公布。对1976年至1985年间儿童恶性肿瘤的发病率进行了研究，以比较氡气接触量≥100贝克勒尔/立方米的邮政编码区域和＜100贝克勒尔/立方米的区域。结果发现，高氡邮政编码区域每百万儿童年发病率为106.7，低氡区域为121.7，两者无显著差异（P = 0.29）。在检查个别肿瘤的发病率时，发现高接触量邮政编码区域的神经母细胞瘤发病率显著增加（P = 0.02），急性髓细胞白血病发病率有非显著性增加。未发现氡气接触与儿童恶性肿瘤总体发病率之间存在关联。
