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[化脓性静脉炎。其后果及治疗]

[Septic phlebitis. Its consequences and its treatment].

作者信息

Vic-Dupont V

出版信息

Phlebologie. 1977 Jan-Mar;30(1):7-14.

PMID:866444
Abstract

Septic phlebitis is characterized clinically by a local syndrome in an arm, the chest or a leg, by an irregular temperature (toothsaw curve), by blood cultures that are simultaneously or successively positive for one or several pathogenic microorganisms, by repeated, multiple infected embolism and by the possibility of endocarditis as a complication. Septic phlebitis occurs either spontaneously (staphylococcosis, syndrome of angina pectoris and infarction), or through secondary infection by secondary microbial colonization of a thrombosis of gynecological or obstetrical origin or, thirdly, as the consequence of venous catheterization (perfusion, pacemaker, explorations). Prevention is based on the selection of the material (silastic piercing catheters), the choice of the site of injection, the observation of strict surgical asepsis and of choice of the fluid injected (no corticoids, nor heparin which inactivates the oligosaccharides). As regards the curative treatment, no use should be made either of heparin or of anti-inflammatory agents (especially no corticoids); first of all, the material that has caused the thrombophlebitis should be withdrawn immediately; secondly, 24 to 36 hours later, a specific antibiotic treatment should be instituted and after two weeks, if still necessary, surgical ligation may be carried out of the inferior vena cava, the subclavian vein or the brachiocephalic venous trunk, depending on the localization of the phlebitis.

摘要

化脓性静脉炎的临床特征为手臂、胸部或腿部出现局部症状,体温不规则(锯齿状曲线),血液培养同时或相继出现一种或多种致病微生物阳性,反复发生多次感染性栓塞,以及可能并发心内膜炎。化脓性静脉炎可自发发生(葡萄球菌感染、心绞痛综合征和梗死),或通过继发于妇科或产科血栓形成的继发性微生物定植引起的继发感染,或作为静脉插管(灌注、起搏器、探查)的后果。预防措施包括选择材料(硅橡胶穿刺导管)、选择注射部位、严格遵守手术无菌操作以及选择注射的液体(不用皮质类固醇,也不用使寡糖失活的肝素)。至于治疗,不应使用肝素或抗炎药(尤其不用皮质类固醇);首先,应立即取出引起血栓性静脉炎的材料;其次,24至36小时后,应开始进行特异性抗生素治疗,两周后,如果仍然必要,可根据静脉炎的部位对下腔静脉、锁骨下静脉或头臂静脉干进行手术结扎。

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