Abplanalp J M, Livingston L, Rose R M, Sandwisch D
Psychosom Med. 1977 May-Jun;39(3):158-77. doi: 10.1097/00006842-197705000-00002.
Twenty-one healthy women were studied during one menstrual cycle in order to determine whether cortisol and growth hormone responsivity to psychological stress was related to estrogen levels. Blood was drawn approximately three times per week for analysis of estradiol, progesterone, cortisol, and human growth hormone. During either the menstrual or intermenstrual phase, each subject participated in an interview that was designed to be mildly stressful. State and trait anxiety were assessed using the Spielberger State-Trait Anxiety Inventory. Anxiety state was measured prior to and immediately following exposure to the psychological stress; trait anxiety was assessed at the end of the study. Cortisol and growth hormone responses to the psychological stress were not related to menstrual cycle phase. Anxiety levels were also independent of menstrual cycle phase. Subjects who displayed significant cortisol and/or growth hormone responsivity to the interview had significantly higher anxiety levels post stress than did nonresponders, although anxiety level prior to the interview was not different for the two groups.
对21名健康女性进行了为期一个月经周期的研究，以确定皮质醇和生长激素对心理压力的反应是否与雌激素水平有关。每周大约采集三次血液，用于分析雌二醇、孕酮、皮质醇和人类生长激素。在月经周期或月经间期，每位受试者都参与了一次旨在产生轻度压力的访谈。使用斯皮尔伯格状态-特质焦虑量表评估状态焦虑和特质焦虑。在暴露于心理压力之前和之后立即测量焦虑状态；在研究结束时评估特质焦虑。皮质醇和生长激素对心理压力的反应与月经周期阶段无关。焦虑水平也与月经周期阶段无关。对访谈表现出显著皮质醇和/或生长激素反应的受试者在压力后焦虑水平明显高于无反应者，尽管两组在访谈前的焦虑水平并无差异。
