Bordet R, Benhadjali J, Destée A, Belabbas A, Libersa C
Service de Neurologie A, CHU, Centre Hospítalier Universitaire, Lille, France.
Clin Neuropharmacol. 1995 Feb;18(1):83-9. doi: 10.1097/00002826-199502000-00012.
In nine patients with orthostatic hypotension due to multiple system atrophy, the effects of octreotide (100 micrograms s.c.), a somatostatin analogue, on blood pressure (BP), heart rate (HR), and norepinephrine (NE) plasma levels after 60 degrees head up tilt test were evaluated by a randomly controlled study. Octreotide increased supine BP, tilt-test duration (+28%), and delay to obtain minimal BP during the 60 degrees head up tilt (+50%). Octreotide changed neither HR nor NE plasma levels.
