Feder H M, Pond K E
Department of Pediatrics, University of Connecticut Health Center, Farmington 06030-3960, USA.
Clin Pediatr (Phila). 1996 Apr;35(4):205-8. doi: 10.1177/000992289603500405.
We report two pediatric patients with recalcitrant staphylococcal infections whose infections resolved when rifampin was added to standard antistaphylococcal therapy. One patient had a post-varicella staphylococcal ulcerative lesion and did not respond to cephalexin alone but did respond when rifampin was added. A second patient had staphylococcal bullous impetigo and did not respond to dicloxacillin or cephalexin but did respond when rifampin was added to the cephalexin. If a patient fails to respond to traditional antistaphylococcal therapy, the addition of rifampin may be beneficial.
我们报告了两名患有顽固性葡萄球菌感染的儿科患者，当在标准抗葡萄球菌治疗中加入利福平后，他们的感染得到了缓解。一名患者患有水痘后葡萄球菌溃疡性病变，单独使用头孢氨苄无反应，但加入利福平后有反应。另一名患者患有葡萄球菌大疱性脓疱病，对双氯西林或头孢氨苄无反应，但在头孢氨苄中加入利福平后有反应。如果患者对传统抗葡萄球菌治疗无反应，加入利福平可能有益。
