Cinquetti M, Marchi D
Cattedra di Pediatria dell'Università-Divisione di Pediatria dell'Ospedale Civile Maggiore di Verona, Italia.
Pediatr Med Chir. 1995 Nov-Dec;17(6):501-7.
The hepatitis C virus is the main causative agent for sporadic as well as parenteral cases of non-A non-B hepatitis. Alpha interferon is a biologically active protein produced by B lymphocytes and monocytes which can be manufactured by recombinant DNA technology. Treatment of chronic hepatitis C with interferon in adults is associated with a sustained response in 20-25% of treated cases. First studies provide encouraging results for the use of interferon in the treatment of chronic hepatitis C in children, but controlled trials using this drug in a larger population of children are needed.
丙型肝炎病毒是散发性以及经肠外途径感染的非甲非乙型肝炎的主要病原体。α干扰素是一种由B淋巴细胞和单核细胞产生的生物活性蛋白，可通过重组DNA技术制造。在成人中，用干扰素治疗慢性丙型肝炎，20% - 25%的治疗病例会出现持续反应。初步研究为干扰素用于治疗儿童慢性丙型肝炎提供了令人鼓舞的结果，但需要在更多儿童群体中进行使用该药物的对照试验。
