Baron R L, Oliver J H, Dodd G D, Nalesnik M, Holbert B L, Carr B
Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Radiology. 1996 May;199(2):505-11. doi: 10.1148/radiology.199.2.8668803.
To evaluate the added value of hepatic arterial-dominant phase (HAP) imaging to portal venous-dominant phase (PVP) imaging in patients with hepatocellular carcinoma (HCC) at computed tomography (CT).
Sixty-six patients with proved HCC underwent biphasic contrast-enhanced CT. HAP and PVP images were obtained at 20-50 and 60-100 seconds, respectively. PVP images were evaluated for the number of HCC foci. Then, HAP images were reviewed to determine whether any additional HCCs were seen.
Three hundred twenty-six tumor foci were seen. HAP images depicted 309 foci (95%) and PVP images 268 (82%). In seven patients (11%), tumor was visible only on HAP images. During the HAP, tumors were hyperattenuating compared with liver in 26 patients, of mixed attenuation in 26, and hypoattenuating in 14 without correlation with histologic appearance. Portal vein thrombosis was identified in 17 of 21 patients on HAP images; in 12 patients, the thrombosis was diagnosed as malignant with neovascularity within the thrombus or diffuse thrombus enhancement.
Use of both HAP and PVP contrast-enhanced CT optimizes the evaluation of patients with or at risk for HCC.
评估在计算机断层扫描（CT）中，肝动脉主导期（HAP）成像相对于门静脉主导期（PVP）成像对肝细胞癌（HCC）患者的附加价值。
66例经证实的HCC患者接受了双期对比增强CT检查。分别在20 - 50秒和60 - 100秒时获得HAP和PVP图像。对PVP图像评估HCC病灶数量。然后，复查HAP图像以确定是否发现任何额外的HCC。
共发现326个肿瘤病灶。HAP图像显示309个病灶（95%），PVP图像显示268个（82%）。7例患者（11%）的肿瘤仅在HAP图像上可见。在HAP期间，26例患者的肿瘤相对于肝脏呈高密度，26例呈混合密度，14例呈低密度，与组织学表现无关。21例患者中有17例在HAP图像上发现门静脉血栓形成；12例患者的血栓被诊断为恶性，血栓内有新生血管或弥漫性血栓强化。
使用HAP和PVP对比增强CT可优化对HCC患者或有HCC风险患者的评估。
