[草酸盐：其在结石形成中的作用及草酸钙结石的成分]

[Oxalate: its role in lithogenesis and composition of calcium oxalate lithiasis].

作者信息

Fernandez Rodríguez A, Arrabal Martín M, Domínguez Molinero J F, Mijan Ortiz J L, Sánchez Tamayo J, Zuluaga Gómez A

机构信息

Servicio de Urología, Hospital Universitario de Granada.

出版信息

Actas Urol Esp. 1995 Sep;19(8):620-6.

PMID:8669329

Abstract

UNLABELLED

A prospective study was conducted on 374 patients with urinary lithiasis, aiming to analyze the participation of oxalate in the lithogenesis and composition of the calcium oxalate calculi, alone or associated to other factors.

METHODOLOGY

Metabolic urinary study of the patient and analysis of calculi with infrared spectrography and optical microscopy.

RESULTS

26.3% patients had hyperoxaluria and 77.5% of the calculi contain calcium oxalate; these are 167 cases of calcium oxalate, 110 of oxalate and calcium phosphate and 13 cases of mixed calcium oxalate and uric acid lithiasis. 43.4% patients with pure monohydrate calcium oxalate calculi have hypercalciuria, 22.6% hyperoxaluria and 19% hyperuricosuria. Dihydrated calcium oxalate calculi are related to high hypercalciuria in 65% cases and to significant hyperoxaluria in 35% cases. 45% patients present a single lithogenic factor, either hypercalciuria (49.6%), hyperoxaluria (20.6%), hyperuricosuria (13.74%), hypocitraturia (9%), urinary infection (1.5%), A.T.R. (2.25%) or acid oliguria (3%).

摘要

未标注

对374例尿路结石患者进行了一项前瞻性研究，旨在分析草酸盐在草酸钙结石的结石形成和成分中的参与情况，单独或与其他因素相关。

方法

对患者进行代谢性尿液研究，并使用红外光谱和光学显微镜对结石进行分析。

结果

26.3%的患者有高草酸尿症，77.5%的结石含有草酸钙；其中草酸钙结石167例，草酸钙和磷酸钙结石110例，草酸钙和尿酸混合结石13例。43.4%的单纯一水草酸钙结石患者有高钙尿症，22.6%有高草酸尿症，19%有高尿酸尿症。二水草酸钙结石在65%的病例中与高钙尿症有关，在35%的病例中与显著的高草酸尿症有关。45%的患者存在单一的致石因素，即高钙尿症（49.6%）、高草酸尿症（20.6%）、高尿酸尿症（13.74%）、低枸橼酸尿症（9%）、泌尿系统感染（1.5%）、肾小管酸中毒（2.25%）或酸性少尿（3%）。