麻醉期间地氟烷的摄取

Uptake of desflurane during anaesthesia.

作者信息

Walker T J, Chakrabarti M K, Lockwood G G

机构信息

Department of Anaesthesia, Hammersmith Hospital, London.

出版信息

Anaesthesia. 1996 Jan;51(1):33-36. doi: 10.1111/j.1365-2044.1996.tb07650.x.

DOI:10.1111/j.1365-2044.1996.tb07650.x

PMID:8669563

Abstract

The amount of desflurane required to maintain an end-expired concentration of 8% was measured in 30 ASA 1 and 2 patients undergoing elective spinal surgery. The anaesthetic was administered using a computer-controlled closed circle system. After an initial period during which the expired concentration of desflurane was stabilised (4 min) the rate of uptake showed a bi-exponential decline. Mean cumulative usage of desflurane was 10.1 ml of liquid at 30 min, 14.8 ml at 60 min, 25.4 ml at 120 min, 35.8 at 180 min.

摘要

在30例接受择期脊柱手术的美国麻醉医师协会（ASA）1级和2级患者中，测量维持呼气末浓度为8%所需的地氟烷量。使用计算机控制的闭环系统给予麻醉。在最初使地氟烷呼气浓度稳定的阶段（4分钟）之后，摄取率呈双指数下降。地氟烷的平均累积用量在30分钟时为10.1毫升液体，60分钟时为14.8毫升，120分钟时为25.4毫升，180分钟时为35.8毫升。