Ngan Kee W D, Lam K K, Twyford C, Gin T
Department of Anaesthesia and Intensive Care, Chinese University, Shatin, Hong Kong.
Anaesth Intensive Care. 1996 Feb;24(1):51-5. doi: 10.1177/0310057X9602400109.
We evaluated a disposable device (Baxter PCA Infusor) for patient-controlled epidural analgesia (PCEA) using pethidine in twenty women after lower segment caesarean section. Efficacy, as measured by visual analogue pain scores, was comparable with historical controls from PCEA studies using electronic devices. Three patients reported inadequate analgesia, attributable in two cases to problems with epidural catheter. PCEA was stopped in one patient because of side-effects. Pethidine consumption ranged from 125 to 1500 mg (median 575 mg) in 48 hours. Plasma concentrations of pethidine varied widely. Disposable devices for PCEA after caesarean section provide an alternative to bolus administration or PCEA using more expensive and cumbersome electronic devices, although we suggest currently available apparatus requires modifications to improve clinical performance.
我们评估了一种一次性装置（百特PCA输注器）用于20名下段剖宫产术后患者自控硬膜外镇痛（PCEA）时使用哌替啶的情况。通过视觉模拟疼痛评分衡量的镇痛效果与既往使用电子装置进行PCEA研究中的对照相当。3名患者报告镇痛不足，其中2例归因于硬膜外导管问题。1例患者因副作用停止了PCEA。48小时内哌替啶用量为125至1500毫克（中位数575毫克）。哌替啶的血浆浓度差异很大。剖宫产术后PCEA的一次性装置为推注给药或使用更昂贵且笨重的电子装置进行PCEA提供了一种替代方法，尽管我们认为目前可用的器械需要改进以提高临床性能。
