Aine C J, Supek S, George J S, Ranken D, Lewine J, Sanders J, Best E, Tiee W, Flynn E R, Wood C C
Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Cereb Cortex. 1996 May-Jun;6(3):354-61. doi: 10.1093/cercor/6.3.354.
Retinotopic mapping strategies similar to those used for invasive electrophysiological studies to identify multiple visual areas in monkeys have been adapted for noninvasive studies in humans, using magnetic recordings of brain activity in conjunction with anatomical magnetic resonance imaging. The retinotopic organization of the primary visual area (V1) in the left hemisphere of human subjects was examined by presenting a small patterned stimuli near the vertical and horizontal meridians in the lower right visual field. In contrast with the classical model of V1 retinotopy, our results suggest that the representation of the horizontal meridian does not necessarily correspond in a one-to-one manner with the base of the calcarine fissure and that some lower field stimuli can activate regions in the lower bank of the fissure. The results also indicate significant individual variability in the details of how V1 maps around the calcarine fissure.
类似于用于侵入性电生理研究以识别猴子多个视觉区域的视网膜拓扑映射策略，已被改编用于人类的非侵入性研究，即结合大脑活动的磁记录与解剖磁共振成像。通过在右下视野的垂直和水平子午线附近呈现小图案刺激，检查了人类受试者左半球初级视觉区（V1）的视网膜拓扑组织。与V1视网膜拓扑的经典模型相反，我们的结果表明，水平子午线的表征不一定与距状裂的底部一一对应，并且一些下视野刺激可以激活裂底部下岸的区域。结果还表明，V1围绕距状裂的映射细节存在显著的个体差异。
