Schnorr J A, Miller H, Davis J R, Hatch K, Seeds J
Department of Obstetrics and Gynecology, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
Am J Perinatol. 1996 Feb;13(2):95-7. doi: 10.1055/s-2007-994300.
Hyperreactio luteinalis is a condition associated with bilateral and, in rare cases, unilateral ovarian enlargement due to theca lutein cysts. Hyperreactio luteinalis is a benign condition, usually found incidentally at cesarean section, which can appear anaplastic and lead to unnecessary ovarian resection. A 21-year-old Hispanic woman, G2P1, presented at 19 weeks with a singleton pregnancy, bilaterally enlarged ovaries, and a normal beta hCG. Over the next four months, her ovaries increased 75% in size with the right ovary becoming entrapped in the pelvis. The patient underwent a primary low transverse cesarean section. The ovaries had an anaplastic appearance and on frozen section revealed multiple benign theca lutein cysts. There are 51 reported cases of hyperreactio luteinalis associated with a normal pregnancy in the literature. It is estimated that approximately 60% of the cases of hyperreactio luteinalis unassociated with trophoblastic disease occur with normal singleton pregnancy. There are multiple benign ovarian lesions including hyperreactio luteinalis that can mimic ovarian neoplasms. Accordingly, it is important to exclude these from the differential diagnosis via a wedge biopsy and frozen section to avoid unnecessary surgical excision.
卵巢黄素化囊肿过度反应是一种与双侧卵巢增大相关的病症，在罕见情况下也可单侧卵巢增大，由黄素囊肿引起。卵巢黄素化囊肿过度反应是一种良性病症，通常在剖宫产时偶然发现，其外观可能呈间变，导致不必要的卵巢切除。一名21岁的西班牙裔女性，孕2产1，孕19周时因单胎妊娠、双侧卵巢增大且β-人绒毛膜促性腺激素正常前来就诊。在接下来的四个月里，她的卵巢大小增加了75%，右侧卵巢被困于盆腔。患者接受了低位横切口剖宫产术。卵巢外观呈间变，冰冻切片显示多个良性黄素囊肿。文献中报道了51例与正常妊娠相关的卵巢黄素化囊肿过度反应病例。据估计，约60%与滋养细胞疾病无关的卵巢黄素化囊肿过度反应病例发生于正常单胎妊娠。包括卵巢黄素化囊肿过度反应在内的多种良性卵巢病变可酷似卵巢肿瘤。因此，通过楔形活检和冰冻切片从鉴别诊断中排除这些病变以避免不必要的手术切除很重要。
