Chaverri Alejandro Pérez, Solis Beatriz Elizabeth Aguilar, Paulín Félix Domínguez, Cárdenas José Eugenio Guerra
Department of Obstetrics and Gynecology, Universidad Autónoma de Tamaulipas, Tampico, Tamaulipas, Mexico.
Department of Obstetrics and Gynecology, "Dr. Carlos Canseco" General Hospital of Tampico, Tampico, Tamaulipas, Mexico.
Case Rep Womens Health. 2018 Dec 29;21:e00094. doi: 10.1016/j.crwh.2018.e00094. eCollection 2019 Jan.
We report a case of hyperreactio luteinalis (HL) and hypothyroidism diagnosed at 13 weeks of pregnancy. A 29-year-old woman with a spontaneous 13-week singleton pregnancy presented with hirsutism and a pelvic mass. Ultrasound showed a viable pregnancy compatible with the gestational age and multiple cystic lesions on both ovaries. Her TSH levels were markedly elevated and diagnostic of hypothyroidism, for which she was treated. Two days after presentation, she had a spontaneous abortion. The products of conception were histologically normal. Follow-up at 3 months showed resolution of the ovarian cysts, and the previously elevated androgen levels were in the normal range. Hyperreactio luteinalis was diagnosed. Her elevated TSH levels may have contributed to hyperreactio luteinalis through the activation of the hCG receptor.
我们报告一例在妊娠13周时诊断出的黄素化囊肿过度反应（HL）和甲状腺功能减退症病例。一名29岁的女性，自然单胎妊娠13周，出现多毛症和盆腔肿块。超声检查显示妊娠存活且与孕周相符，双侧卵巢有多个囊性病变。她的促甲状腺激素（TSH）水平显著升高，诊断为甲状腺功能减退症，并接受了相应治疗。就诊两天后，她发生了自然流产。流产产物的组织学检查正常。3个月后的随访显示卵巢囊肿消退，之前升高的雄激素水平恢复正常范围。诊断为黄素化囊肿过度反应。她升高的TSH水平可能通过激活人绒毛膜促性腺激素（hCG）受体导致了黄素化囊肿过度反应。
