van de Kelft E J, van Goethem J W, de La Porte C, Verlooy J S
Department of Neurosurgery, Universitair Ziekenhuis Antwerpen, University of Antwerp, Belgium.
Br J Neurosurg. 1996 Feb;10(1):41-9.
A prospective study was undertaken to establish the normal spectrum of early gadolinium-enhanced magnetic resonance (MR) imaging findings in patients who had resolution of symptoms after lumbar discectomy. Thirty-four patients underwent MR examinations 6 weeks and 6 months after lumbar discectomy on a 1.5 T superconducting unit, including sagittal and axial spin-echo (SE) T1-weighted images before and after intravenous administration of gadolinium-DTPA, as well as sagittal turbo (or fast-) SE T2-weighted images. All patients showed soft tissue enhancement along the surgical track in the subcutaneous soft tissue lateral to the spinous process and in the epidural space. There was only minimal (45%) or no (55%) mass effect on the dural sac associated with epidural scar formation 6 months after surgery, but often the nerve root at the operative level was surrounded by this enhancing tissue. Facet joint enhancement was seen in most patients 6 weeks (63%) and 6 months (53%) after surgery. Intrathecal nerve root enhancement was observed in six patients, 6 weeks after surgery. Nine patients (20%) had residual mass effect on the neural elements with an enhancement pattern suggestive of a disc fragment. Enhancement of the intervertebral space was seen in 67% of patients 6 weeks after surgery and in 86% of patients after 6 months. It may be concluded that, despite the use of gadolinium-DTPA, MR studies obtained in the initial postoperative period are difficult to interpret, because of the normal sequence of changes. Consequently, the clinical picture still remains the major indicator for recurrent surgery.
进行了一项前瞻性研究,以确定腰椎间盘切除术后症状缓解患者早期钆增强磁共振(MR)成像结果的正常范围。34例患者在腰椎间盘切除术后6周和6个月接受了1.5T超导单元的MR检查,包括静脉注射钆喷酸葡胺前后的矢状位和轴位自旋回波(SE)T1加权图像,以及矢状位快速自旋回波(FSE)T2加权图像。所有患者在棘突旁皮下软组织和硬膜外间隙的手术通道处均显示软组织强化。术后6个月,硬膜外瘢痕形成对硬膜囊仅有轻微(45%)或无(55%)占位效应,但手术节段的神经根常被这种强化组织包绕。大多数患者在术后6周(63%)和6个月(53%)可见小关节强化。术后6周,6例患者观察到鞘内神经根强化。9例患者(20%)对神经结构有残留占位效应,强化模式提示椎间盘碎片。67%的患者在术后6周和86%的患者在术后6个月可见椎间隙强化。可以得出结论,尽管使用了钆喷酸葡胺,但由于术后早期变化的正常顺序,术后初期获得的MR研究结果难以解释。因此,临床表现仍然是再次手术的主要指标。