Coggon D, Inskip H, Winter P, Pannett B
MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, UK.
Occup Med (Lond). 1996 Feb;46(1):69-70. doi: 10.1093/occmed/46.1.69.
The hazard of scrotal cancer from cutting oils was first recognized in the 1950s, and led to various control measures including the introduction of solvent refined oils, use of splash guards, provision of protective clothing and washing facilities and education of workers to encourage early detection and treatment of tumours. To assess how effective these controls have been, we have analyzed occupational mortality from scrotal cancer in England and Wales during 1979-80 and 1982-90. Over this 11-year period 85 deaths were attributed to the disease in man aged 20-74. This represents a reduction in mortality from the 1960s. Significantly elevated proportional mortality ratios (PMRs) were found in press and machine tool setters (PMR 1,678, five deaths), centre lathe turners (PMR 1,099, three deaths) and machine tool operators (PMR 303, eight deaths), but all of the metal machinists who died of scrotal cancer had been born before 1930, and could have worked with cutting oils before controls were introduced. These findings are reassuring, but continued monitoring of scrotal cancer incidence and mortality is required.
切削油导致阴囊癌的危害在20世纪50年代首次被认识到，并引发了各种控制措施，包括引入溶剂精制油、使用防溅罩、提供防护服和洗涤设施，以及对工人进行教育以鼓励早期发现和治疗肿瘤。为了评估这些控制措施的效果，我们分析了1979 - 1980年和1982 - 1990年期间英格兰和威尔士阴囊癌的职业死亡率。在这11年期间，85例死亡归因于20 - 74岁男性的这种疾病。这表明死亡率较20世纪60年代有所下降。在印刷工人和机床安装工（比例死亡率1678，5例死亡）、中心车床车工（比例死亡率1099，3例死亡）和机床操作员（比例死亡率303，8例死亡）中发现比例死亡率显著升高，但所有死于阴囊癌的金属机械师均出生于1930年之前，并且可能在控制措施实施之前就接触过切削油。这些发现令人安心，但仍需持续监测阴囊癌的发病率和死亡率。
