Baris D, Armstrong B G
Department of Occupational Health, McGill University, Montréal, Québec, Canada.
Occup Environ Med. 1996 May;53(5):334-8. doi: 10.1136/oem.53.5.334.
To investigate how closely the variables of exposures to magnetic fields based on the last job held in an electrical utility in Québec, Canada, compared with those based on the workers' entire employment history with the company.
In large cohort studies, the last job held is often used to assign exposure to the study subjects. Exposure was assigned in this way for a mortality study of a cohort of electrical utility workers in Québec. For the present study, a sample of the cohort was used to compare the exposure estimates obtained from the last job with those obtained from full work histories.
The correlations between indices based on the last job and on all jobs varied between 0.75 and 0.78. The mean was slightly lower when only the last job was used. The last job was particularly good in identifying the most highly exposed people (for the exposure cut off point of 90th percentile for the last job and for all jobs, sensitivity = 0.69, specificity = 0.97, kappa = 0.66). The results suggest that although not all workers starting in highly exposed jobs stayed in them, it seemed that the workers who ended their working life in highly exposed jobs had stayed in these jobs throughout their working life.
The results indicated some (but not catastrophic) loss of information when estimates of exposure were based on the last job only.
研究基于加拿大魁北克省一家电力公司员工最后一份工作所确定的磁场暴露变量,与基于该员工在公司的整个工作经历所确定的变量之间的接近程度。
在大型队列研究中,通常使用最后一份工作来确定研究对象的暴露情况。在对魁北克省一组电力公司员工的死亡率研究中,就是以这种方式确定暴露情况的。在本研究中,从该队列中抽取了一个样本,以比较根据最后一份工作得出的暴露估计值与根据完整工作经历得出的暴露估计值。
基于最后一份工作和所有工作的指数之间的相关性在0.75至0.78之间。仅使用最后一份工作时,平均值略低。最后一份工作在识别暴露程度最高的人群方面表现特别出色(对于最后一份工作和所有工作的第90百分位数的暴露截止点,灵敏度=0.69,特异度=0.97,kappa=0.66)。结果表明,虽然并非所有开始从事高暴露工作的工人都一直从事这些工作,但似乎在高暴露工作中结束职业生涯的工人在其整个工作生涯中都一直从事这些工作。
结果表明,仅基于最后一份工作来估计暴露情况时,会有一些(但并非灾难性的)信息损失。