[评估硫化铜镍矿粉尘致癌作用的实验研究]
[Experimental studies evaluating oncogenic effects of copper-nickel sulfide ore dust].
作者信息
Borisenkova R V, Pylev L N, Lutsenko L A, Lipatov G Ia, Beresneva O Iu, Gvozdeva L L
出版信息
Med Tr Prom Ekol. 1996(2):10-3.
PMID:8673392
Abstract
The experiments on animals studied mutagenic activity of copper-nickel sulfide ore dust. Micronucleus test proved mild mutagenic activity of the ore under study. Chronic inhalation of the dust induced malignancies (mostly lung tumors and leukoses) in 52% of the experimental Wistar rats, that could be caused by dissolution of the dust components in the body fluids.
摘要
对动物进行的实验研究了硫化铜镍矿粉尘的致突变活性。微核试验证明了所研究矿石具有轻度致突变活性。长期吸入该粉尘导致52%的实验用Wistar大鼠发生恶性肿瘤（主要是肺癌和白血病），这可能是由于粉尘成分在体液中溶解所致。
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