Liberski P P, Barcikowska M
Laboratory of Electron Microscopy and Neuropathology, School of Medicine, Lódź.
Folia Neuropathol. 1995;33(4):207-14.
We review here current data on congophilic amyloid angiopathy (congophilic angiopathy) or cerebral amyloid angiopathy in both transmissible and non-transmissible cerebral amyloidoses. A beta peptide is the amyloid in congophilic angiopathy of Alzheimer's disease, and in majority of cases of Creutzfeld-Jakob disease and Gerstmann-Sträussler-Scheinker disease. A variant of Cystatin C is the amyloid in hereditary cerebral hemorrhage with amyloidosis-Icelandic type. The only exception is a curious GSS-like family from Japan characterized by 145 stop codon at the PRNP gene. Both molecular pathology and neuropathology are covered by this review.
在此，我们回顾了关于可传播性和非传播性脑淀粉样变性中嗜刚果红性淀粉样血管病（嗜刚果红血管病）或脑淀粉样血管病的当前数据。β肽是阿尔茨海默病嗜刚果红性淀粉样血管病以及大多数克雅氏病和格斯特曼-施特劳斯勒-谢inker病病例中的淀粉样蛋白。胱抑素C的一种变体是冰岛型遗传性脑出血伴淀粉样变性中的淀粉样蛋白。唯一的例外是一个来自日本的奇特的类似格斯特曼-施特劳斯勒-谢inker病的家族，其特征是PRNP基因存在145位终止密码子。本综述涵盖了分子病理学和神经病理学。
