Savoia D, Ricatto I, Millesimo M, De Intinis G, Daglio C
Department of Clinical and Biological Sciences, University of Torino, Italy.
New Microbiol. 1996 Jan;19(1):59-66.
A one-year (1993) survey of the distribution of pathogens causing respiratory and urinary infections and their antimicrobial susceptibility was performed. The most common bacteria isolated from the lower respiratory tract of patients in a district general hospital were Pseudomonas aeruginosa (35.9%) and Staphylococcus aureus (21.4%). About half of the Pseudomonas strains revealed a resistance to imipenem and gentamicin, whereas almost all Staphylococcus strains were resistant to penicillin G. The most common isolates from urine of in and out-patients were Escherichia coli (32.3% and 39.8%) and Enterococcus faecalis (16.6% and 14.2%). Escherichia coli strains were largely susceptible to almost all chemoantibiotics tested, whereas Enterococcus faecalis demonstrated a high resistance pattern. Pseudomonas aeruginosa isolated from urine were more sensitive to chemoantibiotics than respiratory strains and the susceptibility of Staphylococcus aureus isolated from hospitalized or out-patients was different. A periodic monitoring system devised to give information about the circulation of bacteria and the chemoantibiotic resistance in a local context would be useful to assess the local trends and select drugs for therapy.
对引起呼吸道和泌尿道感染的病原体分布及其抗菌药敏性进行了为期一年(1993年)的调查。在一家地区综合医院患者的下呼吸道分离出的最常见细菌是铜绿假单胞菌(35.9%)和金黄色葡萄球菌(21.4%)。约一半的铜绿假单胞菌菌株对亚胺培南和庆大霉素耐药,而几乎所有金黄色葡萄球菌菌株对青霉素G耐药。门诊和住院患者尿液中最常见的分离菌是大肠埃希菌(分别为32.3%和39.8%)和粪肠球菌(分别为16.6%和14.2%)。大肠埃希菌菌株对几乎所有测试的化学抗生素大多敏感,而粪肠球菌表现出高度耐药模式。从尿液中分离出的铜绿假单胞菌比呼吸道菌株对化学抗生素更敏感,且从住院患者或门诊患者中分离出的金黄色葡萄球菌的药敏性有所不同。设计一个定期监测系统以提供有关当地细菌传播和化学抗生素耐药性的信息,将有助于评估当地趋势并选择治疗药物。