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痰培养中的细菌病原体(非分枝杆菌)及抗菌药敏情况。

Bacterial pathogens (non-Mycobacterium) from sputum culture and antimicrobial susceptibility.

作者信息

Srifuengfung S, Sangsawang M, Komolpis P, Dhiraputra C, Chompanee B

机构信息

Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 1998 Mar;29(1):96-9.

PMID:9740278
Abstract

Sputum culture of patients at Siriraj Hospital, Bangkok was 49.84% positive for bacterial pathogens in 1994 and 40.95% in 1995. The average incidence of gram-negative rods was 3.11 fold more than the combination of gram-positive cocci and gram-negative cocci. The most common gram-negative rod was Pseudomonas aeruginosa, followed by either Klebsiella pneumoniae or Acinetobacter anitratus depending on year. The most common coccus was Staphylococcus aureus. From both years, the number of Haemophilus influenzae, Streptococcus pneumoniae, Burkholderia pseudomallei and Nocardia spp isolated were 122, 93, 13 and 11 strains respectively. For antimicrobial susceptibility, P. aeruginosa was sensitive to ceftazidime, imipenem, gentamicin, amikacin, netilmicin, ciprofloxacin (range 56-89%). S. aureus (MSSA) was sensitive to common used drugs. S. aureus (MRSA) was sensitive to co-trimoxazole, fosfomycin, vancomycin (range 57-100%) and resistant to most drugs.

摘要

曼谷诗里拉吉医院患者的痰液培养结果显示,1994年细菌病原体阳性率为49.84%,1995年为40.95%。革兰氏阴性杆菌的平均发病率比革兰氏阳性球菌和革兰氏阴性球菌的总和高3.11倍。最常见的革兰氏阴性杆菌是铜绿假单胞菌,其次是肺炎克雷伯菌或鲍曼不动杆菌(取决于年份)。最常见的球菌是金黄色葡萄球菌。这两年中,分离出的流感嗜血杆菌、肺炎链球菌、类鼻疽伯克霍尔德菌和诺卡氏菌属的菌株数分别为122株、93株、13株和11株。在抗菌药敏性方面,铜绿假单胞菌对头孢他啶、亚胺培南、庆大霉素、阿米卡星、奈替米星、环丙沙星敏感(敏感率为56 - 89%)。金黄色葡萄球菌(甲氧西林敏感金黄色葡萄球菌)对常用药物敏感。金黄色葡萄球菌(耐甲氧西林金黄色葡萄球菌)对复方新诺明、磷霉素、万古霉素敏感(敏感率为57 - 100%),对大多数药物耐药。

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