Bhatnagar A, Lahoti D, Singh A K, Shankar L R, Sharma B, Singh T
Department of Nuclear Medicine, Institute of Nuclear Medicine and Allied Sciences, Delhi, India.
Clin Nucl Med. 1995 Dec;20(12):1070-3. doi: 10.1097/00003072-199512000-00007.
The authors performed abdominal scintigraphy using intravenously administered Tc-99m dextran in a patient with protein losing enteropathy. The study revealed abnormal leakage of the radiotracer in the left lumber area that moved over time in a pattern suggestive of small intestinal transit. Besides being a nonprotein and having long stay in intravascular compartment, the macromolecule may have many advantages over Tc-99m human serum albumin, the current radiotracer of choice for imaging intestinal protein loss.
作者对一名患有蛋白丢失性肠病的患者静脉注射锝-99m右旋糖酐后进行了腹部闪烁扫描。研究显示,放射性示踪剂在左腰部区域异常渗漏,且随时间移动,呈现出小肠转运的模式。除了是非蛋白质且在血管腔内停留时间长外,这种大分子相对于锝-99m人血清白蛋白(目前用于成像肠道蛋白丢失的放射性示踪剂)可能具有许多优势。