间歇性类固醇疗法对抗精子抗体水平的影响。
The effect of intermittent steroid therapy on anti-sperm antibody levels.
作者信息
Keane D, Jenkins D M, Higgins T, O'Neill M, Mulcahy M F, Ferriss J B
机构信息
Department of Zoology, University College Cork, Ireland.
出版信息
Eur J Obstet Gynecol Reprod Biol. 1995 Nov;63(1):75-9. doi: 10.1016/0301-2115(95)02217-u.
Sperm-bound antisperm antibody levels were measured in 10 males in subfertile partnerships who were treated with high dose intermittent prednisolone therapy over a period up to 9 months. Antibody levels fell in all patients during therapy, although a transient rise occurred after 2-4 months. There were low treatment complication rates. Four pregnancies occurred during the treatment of the 10 patients. There was no correlation between pregnancy and change in antibody.
对10对患有生育力低下的伴侣关系中的男性进行了精子结合抗精子抗体水平的检测，这些男性接受了长达9个月的高剂量间歇性泼尼松龙治疗。治疗期间所有患者的抗体水平均下降，尽管在2 - 4个月后出现了短暂上升。治疗并发症发生率较低。在这10名患者的治疗期间有4例怀孕。怀孕与抗体变化之间没有相关性。
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